肆客足球

?DNA amplification an??d asse???mbly 

???Legacy DNA cloning method??s and i?nvestigating new methods to marry isothermal amplification and automation of cloning. 

Protein eng??in?e????ering

Delivering a superior enzyme for the efficient production of prebiotic fructooligosaccharide sweeteners. 

Rea??d ?mo??re 

?In vitro transcription and cell-free protein expression

?Our laboratory utilizes an integrated platform for both in vitro transcription and cell-free protein synthesis, enabling the seamless production of functional proteins from DNA templates. This system allows for rapid, efficient protein expression without the need for living cells, facilitating flexible experimental design and accelerating research in protein function, enzyme activity, and synthetic biology applications. 

?Yeast bioengineering?? 

??????An innovative yeast screening tool has been developed to identify "jackpot" clones in a protein-agnostic manner. This method allows for the rapid and cost-effective evaluation of thousands of engineered yeast strains, ultimately pinpointing a select few to undergo more rigorous testing to assess their potential for specific applications. ?The team has deployed this tool to develop technologies to produce in vitro transcription enzymes used to manufacture mRNA vaccines. 

??Mammalian cell culture??

?????????????Mammalian cell culture protocols are in place, including the transfection of mRNA to assess the functionality of in vitro transcription processes.  Beyond this, our mammalian cell culture facility is equipped for a wide range of studies, inlcuding microbial-mammalian cell co-culture to study host-pathogen interactions,???evaluating drug efficacy and toxicity, and producing biological products like antibodies ????and vaccines.